Empower Tip: Empower CDS User Question

In this tip for Empower Chromatography Data System (CDS), we will answer another Empower user question.

Q: Is it possible to calculate signal-to-noise ratio using a blank from a Sample Set other than the one which has the samples of interest?

Let’s see how it is done.

From the Sample Sets tab, highlight the Sample Sets that contain the data you want to work with. Right-click and select ‘View As, Channels’.

On the Channels tab, have a View Filter already created that includes Sample Set Name. Highlight the ‘Blank’ from one Sample Set and ‘Channels’ of interest from the other Sample Set. Then create a Process Only Sample Set. Note: Refer to Tip 237 to learn how to create Process Only Sample Sets.

Make sure the Processing Method has ‘Calculate USP, EP and JP s/n’ selected along with ‘Use noise centered on peak region in blank injection’. [figures 3]

Once the data is processed, you will see the ‘Blank’.

The peaks in the sample have both the ‘USP signal to noise (s/n)’ and ‘USP noise’ calculated for each peak and can be displayed in the Peaks table.

It’s that easy!