Empower Tip: Changes to the USP chapter <621>

Now let’s review an important tip discussing the changes to the USP chapter <621> as they relate to Empower:

USP Resolution is now called Resolution and is calculated using peak width at half height. Using current versions of Empower you can report USP Resolution (HH) or a Custom Field.

Relative Resolution should also be calculated using peak width at half height. If you select USP in the Processing Method with current versions of Empower, it does use the peak width at half height for this calculation.

USP Plate Count is now called Plate Number and is calculated using peak width at half height. Using current versions of Empower you can report EP Plate Count or a Custom Field.

STEP 3USP Tailing is now called Symmetry Factor and there is no change to the calculation.

USP Signal-to-Noise ratio has no change to the formula, however, the half-height multiplier is now 20 which for current versions of Empower, can be changed from 5 to 20 in the Processing Method (figures 2 & 5).

It’s that easy!