Empower Tip: Baseline Noise

In this tip for Empower Chromatography Data System (CDS), we will continue our series on Baseline Noise and discuss Detector Noise.

The calculation of Detector Noise is enabled in the Empower Processing Method on the Noise and Drift tab. You specify a start time, a stop time, and a segment width over which to calculate average Detector Noise.

For Detector Noise a best-fit line is created, the residual amount is calculated for each data point, these residuals are summed then squared, and then averaged. The square root of the average is the resulting Root Mean Squared noise that is reported by Empower.

Average Detector Noise is the same calculation as described in Step 2 for the Detector Noise calculation, but the calculation is performed independently for each segment. These segment calculations are then averaged to give the final reported average Detector Noise.

It’s that easy!