Empower Tip: Empower CDS User Question

In this tip for Empower Chromatography Data System (CDS), we will answer two Empower user questions about processing MS data.

Question 1: Is it better to apply smoothing in the Processing Method or in the Method Set as part of the derived channel?

The answer depends based on a few scenarios.

If you are processing several 2D channels all with the same Processing Method but want to apply different levels of smoothing, you could put the smoothing in the derived channels within the method set.

On the other hand, if you are smoothing all channels at the same level, then you could put it in either the processing method or the derived channels in the method set. .

Question 2: Is there a way to reduce the processed MS signal to a smaller range post acquisition? I scanned from 50 to 1200 Da and want to limit the range post acquisition

Another great question.

You can derive a channel called ‘MS : Calculated’ which allows you to enter a smaller mass range for processing.

Here is an example of a channel processed over the full acquired mass range versus the smaller mass range.

It’s that easy!